Saturday, December 11, 2010
scientists create mice from two fathers
WASHINGTON (AFP) – US scientists get used originate cell technology to make mice via two dads, an advance that they say could help maintain endangered species and even help same-sex young couples have their own genetic children at some point.
According into the study printed Wednesday while in the journal Biology associated with Reproduction, reproductive researchers in Texas were able to manipulate cells coming from a male (XY) rabbit fetus to create an induced pluripotent leaves (iPS) personal line.
These iPS cells are older cells that contain undergone a few genetic reprogramming so that they can enter a good embryonic originate cell-like assert.
Some on the cells which were grown using this new brand spontaneously lost their FUL chromosome, resorting them in XO solar cells.
Those XO cellular material were which is injected into embryos coming from donor womans mice in addition to transplanted directly into surrogate computer mouse moms whom gave beginning to toddlers with one particular X chromosome from your original men mouse.
All those babies mature and later mated together with normal male mice. The offspring, each male in addition to female, exhibited genetic money from two fathers.
Your study appeared to be led by simply Richard UR. Berhringer in the MD Anderson Cancer tumor Center.
Researchers claimed that using a variation of these technique, "it will also work possible to make sperm at a female donor along with produce feasible male plus female progeny with two parents. "
Nevertheless, the analyze cautioned that this ability in order to replicate this findings around humans was quite a distance off.
The "generation with human iPS tissue still needs significant refinements previous to their use for healing purposes, " this study explained.
Previous research has found methods of create mice with no fathers in any respect, as properly as approaches to create mice with 2 mothers.
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